Syphilis Serology
The Syphilis Serology Unit serves primarily
as the reference laboratory for the
confirmation of sera results that are
reactive by any serological test for
syphilis. The Venereal Disease Research
Laboratory (VDRL) test is performed on all
sera and spinal fluids submitted to the
Syphilis Serology Unit. If the result is
weakly reactive (WR) or (R) a confirmatory
test that is specific for Treponema
pallidum antibody (TP-PA) is performed.
The TP-PA is not routinely
performed on sera that are non-reactive.
Exceptions can be made but must be
communicated to the Serology Unit by
checking the Reference box on the
requisition slip.
The VDRL is used to evaluate
the results of treatment therapy as it tends
to revert to a lower titer or non-reactive
after treatment. The TP-PA will remain
positive after treatment.
Microbiology Forms
For further information please refer to the
PHL Directory of Services
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