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Enterohemorrhagic E. coli (EHEC)


Cause: Shiga toxin-producing E. coli strains (STEC) including E. coli O157:H7.

Illness and treatment: Symptoms include abdominal cramping and severe or bloody diarrhea, usually without fever. Serious complications include hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP). Most persons will recover without treatment. Treating EHEC diarrhea with antibiotics may increase the risk of developing HUS.

Sources: Cattle are the most important source, although other animals including deer and horses may also carry EHEC. Other known sources are unpasteurized milk, undercooked ground beef and more recently, contaminated raw produce. There can be person-to-person transmission, but most cases are due to ingesting contaminated food or water.

Additional risks: Children under 5 years of age are diagnosed most frequently and are at the greatest risk of developing HUS.

Prevention: Wash hands thoroughly after contact with farm animals, visiting farm environments, and handling raw meat. Thoroughly cook ground beef and venison and wash preparation areas to avoid contaminating other foods. Wash produce thoroughly before eating.

Recent Washington trends: For the past several years there have been about 130 - 190 reports each year. EHEC has a seasonal pattern. Most cases occur during summer and fall months.

2008: 189 cases were reported (2.9 cases/100,000 population) with one death. Cases were most frequently diagnosed in children ages 1 to 4 years of age. Hemolytic uremic syndrome as a complication of EHEC was reported in 12 cases. 21 (12.8%) of all confirmed and serotyped EHEC cases were non-O157:H7 (8 O26:H11; 7 O103:H2; 2 O121:H19; one each O26:NM, O103:H11, O111:NM, and O145:NM).

Purpose of Reporting and Surveillance

  • To determine if there is a source of infection of public health concern (e.g., contaminated ground beef) and to stop transmission from such a source.

  • When the source of infection appears to pose a risk to only a few individuals (e.g., a private water supply), to inform those individuals how they can reduce their risk of exposure.

  • To assess the risk of the case transmitting infection to others, and to prevent such transmission.

  • To identify outbreaks and other undiagnosed cases.

Legal Reporting Requirements

  • Health care providers: immediately notifiable to local health jurisdiction.

  • Hospitals: immediately notifiable to local health jurisdiction.

  • Laboratories: identification of Shiga toxin-producing organism notifiable to local health jurisdiction within 2 workdays; submission of stool specimen or isolate to the Washington State Department of Health Public Health Laboratories required.

  • Local health jurisdictions: notifiable to DOH Communicable Disease Epidemiology Section within 7 days of case investigation completion or summary information required within 21 days.

Last update
November 2009

E. coli Resources

General Information

Fact Sheet
(Web format)
E. coli
Incidence Rates

(PDF format)

Reporting Forms

E. coli
Reporting Form

(PDF Format)

Public Health and Health Care

Surveillance and Reporting Guidelines
(PDF format, 52KB)

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Communicable Disease Epidemiology
Office of Epidemiology
Washington State Department of Health
MS: K17-9, 1610 NE 150th St.
Shoreline, WA 98155-9701

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Phone (206) 418-5500

FAX (206) 418-5515

24-hour contact (inside Washington State only)  1-877-539-4344

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